Grey’s Anatomy has torrid relationships down to a science, but when Derek (Patrick Dempsey) and Meredith (Ellen Pompeo) finally got together, fans could breathe easy. Sure, they still had their ups and downs — the hospital shooting, her tampering with the clinical trial, his need for speed — but at least the MerDer ‘shippers can rest easy that executive producer Shonda Rhimes won’t — crosses fingers, just in case — ever break them up again.

Mommy and Daddy Issues: We grade the parents of fall TV

However, it’s a different story for Mer’s best friend Cristina (Sandra Oh), who has been…

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• Kevin McKidd
• Patrick Dempsey
• Sandra Oh
• Grey’s Anatomy
• Kim Raver
• Ellen Pompeo
• Shonda Rhimes