Officials say at least 63 people were killed and another 180 wounded when the bomb exploded in a vegetable market in Quetta.
A senior police officer says the bomb was detonated by remote control in a mostly Shiite neighborhood. The blast left many victims buried under rubble, but it’s uncertain how many.
Local residents rushed the victims to three different area hospitals. Many of the wounded are said to be in critical condition.
It was the deadliest incident since bombings in the same city killed 86 people earlier this year. That incident led to days of protest that eventually toppled the local government.
Shiites are a minority in Pakistan, where Sunni Muslims dominate. They have been increasingly targeted for attacks by militant groups who view them as heretics and non-Muslims.